The dried out flowers and fallen leaves are also smoked to soothe epilepsy. The fallen leaves and also flowers are reported to create a light blissful effect when smoked and also have actually been said to have a similar, although much less potent, psychoactive result to marijuana. To amalgamate the botanical aspects, ethnopharmacology, phytochemistry, biological activity, poisoning and also business elements of the scientific literary works readily available on Leonotis leonurus. Leonotis leonurus has primarily terpenoids, particularly labdane diterpenes, the major diterpene reported is marrubiin. Various other compounds have been reported by some writers to have been separated from the plant, including, in the prominent literary works only, the mildly psychedelic alkaloid, leonurine. Leonurine has nonetheless, never been reported by any type of clinical evaluation of the extracts of L. leonurus. Regardless of the publication of numerous documents on L. leonurus, there is still, nonetheless, the requirement for conclusive research study and explanation of various other compounds, consisting of alkaloids as well as important oils from leonotis leonurus, as well as from other plant parts, such as the roots which are thoroughly used in conventional medicine. The typical use by cigarette smoking additionally needs more examination as to just how the chemistry as well as task are influenced by this kind of administration. Research has actually proven the psychedelic impacts of the unrefined essence of L. leonurus, however verification of the visibility of psychedelic compounds, in addition to isolation and characterisation, is still called for. Purposeful deterioration of L. leonurus with synthetic cannabinoids has been reported recently, in an effort to promote the marketing of these illegal compounds, highlighting the need for refinement of proper quality assurance procedures to make certain safety and quality. Much job is for that reason still needed on the element of quality control to make certain safety and security, high quality and efficacy of the product provided to patients, as this plant is commonly used in South Africa as a standard medication. Readily available plant resources provide a feasible alternative for phytochemical study, particularly when it come to the suitable recognition of the plant material in order to recognize and delimit carefully associated types such as L. leonurus and L. nepetifolia which are really similar in habit.